Donald MacDonald had a long and varied career in the entertainment industry, showcasing his talent across several decades. Early on, Donald MacDonald made his mark in film with roles in notable projects like Who Cares (1918), the dramatic adaptation Lorna Doone (1922) starring Madge Bellamy, and the introspective These Thirty Years (1934). As time went on, Donald MacDonald continued to build his resume, appearing in the lighthearted comedy Ma and Pa Kettle at Home (1954) alongside Marjorie Main.

Throughout the 1950s and 1960s, Donald MacDonald remained active, taking part in exciting productions such as Burt Lancaster’s action-packed The Kentuckian (1955) and Hugh O’Brian’s western The Brass Legend (1956). His enduring presence in film carried into the later years of his life, where Donald MacDonald embraced diverse roles in projects like the suspenseful Jaws 2 (1978) with Roy Scheider, the heartfelt The Best of Friends (1981), and the socially conscious TV movie Date Rape (ABC, 1988–89).

Even in the later stages of his career, Donald MacDonald stayed committed to his craft. One of his more recent appearances was in Martin Donovan’s comedic drama Collaborator (2012), a testament to Donald MacDonald’s lasting passion for storytelling and performance.