Alexis Arquette was a talented character actor and prominent transgender activist, known for being part of the well-known Arquette family, which also included Rosanna, Patricia, and David. Her performance as a drag queen living in the slums in Last Exit to Brooklyn (1989) brought her critical praise early in her career. Alexis went on to appear in several notable films and shows, including small but memorable roles in Buffy the Vampire Slayer (1992), Threesome (1994), and Pulp Fiction (1994).
She later took on leading roles in LGBTQ+-themed independent films such as Never Met Picasso (1996) and I Think I Do (1997). Her presence in mainstream cinema grew with standout performances in popular comedies like The Wedding Singer (1997) and Bride of Chucky (1998). Alexis Arquette was also a familiar face on television, appearing multiple times on Xena: Warrior Princess (syndicated, 1995–2001) and Friends (NBC, 1994–2004).
In addition to her acting career, she was known for her drag persona “Eva Destruction” and played a key role in producing and starring in Killer Drag Queens on Dope (2003). Alexis became more visible in the public eye when she shared her personal journey of gender transition on reality shows like The Surreal Life, which aired first on The WB and later on VH1. Her life and experiences were further explored in the documentary Alexis Arquette: She’s My Brother (2007).
Throughout her career, Alexis Arquette was celebrated for her versatility, bringing depth and authenticity to characters that spanned the gender spectrum. Her unique voice and perspective made her a standout figure in both independent and mainstream entertainment. Alexis passed away on September 11, 2016, at the age of 47, surrounded by loved ones at her home.
When it comes to Alexis Arquette’s filmography, one name that consistently stands out is Of Mice and Men (1992)—widely regarded as Alexis Arquette’s highest-rated movie. This critically acclaimed adaptation truly showcased Alexis Arquette’s talent and remains a highlight in their acting career. On the other end of the spectrum, The Price of Air (2000) tends to receive much less favorable reviews, making it Alexis Arquette’s lowest-rated film to date. While opinions on movies can vary, it’s clear that Alexis Arquette gave memorable performances across a diverse range of roles. Still, fans often point to Of Mice and Men (1992) as the definitive standout when discussing Alexis Arquette’s impact in cinema.